MedGemma Technical Report

Andrew Sellergren, Sahar Kazemzadeh, Tiam Jaroensri, Atilla Kiraly, Madeleine Traverse, Timo Kohlberger, Shawn Xu, Fayaz Jamil, Cían Hughes, Charles Lau, Justin Chen, Fereshteh Mahvar, Liron Yatziv, Tiffany Chen, Bram Sterling, Stefanie Anna Baby, Susanna Maria Baby, Jeremy Lai, Samuel Schmidgall, Lu Yang, Kejia Chen, Per Bjornsson, Shashir Reddy, Ryan Brush, Kenneth Philbrick, Mercy Asiedu, Ines Mezerreg, Howard Hu, Howard Yang, Richa Tiwari, Sunny Jansen, Preeti Singh, Yun Liu, Shekoofeh Azizi, Aishwarya Kamath, Johan Ferret, Shreya Pathak, Nino Vieillard, Ramona Merhej, Sarah Perrin, Tatiana Matejovicova, Alexandre Ramé, Morgane Riviere, Louis Rouillard, Thomas Mesnard, Geoffrey Cideron, Jean-bastien Grill, Sabela Ramos, Edouard Yvinec, Michelle Casbon, Elena Buchatskaya, Jean-Baptiste Alayrac, Dmitry Lepikhin, Vlad Feinberg, Sebastian Borgeaud, Alek Andreev, Cassidy Hardin, Robert Dadashi, Léonard Hussenot, Armand Joulin, Olivier Bachem, Yossi Matias, Katherine Chou, Avinatan Hassidim, Kavi Goel, Clement Farabet, Joelle Barral, Tris Warkentin, Jonathon Shlens, David Fleet, Victor Cotruta, Omar Sanseviero, Gus Martins, Phoebe Kirk, Anand Rao, Shravya Shetty, David F. Steiner, Can Kirmizibayrak, Rory Pilgrim, Daniel Golden, Lin Yang

Artificial intelligence (AI) has significant potential in healthcare applications, but its training and deployment faces challenges due to healthcare's diverse data, complex tasks, and the need to preserve privacy. Foundation models that perform well on medical tasks and require less task-specific tuning data are critical to accelerate the development of healthcare AI applications. We introduce MedGemma, a collection of medical vision-language foundation models based on Gemma 3 4B and 27B. MedGemma demonstrates advanced medical understanding and reasoning on images and text, significantly exceeding the performance of similar-sized generative models and approaching the performance of task-specific models, while maintaining the general capabilities of the Gemma 3 base models. For out-of-distribution tasks, MedGemma achieves 2.6-10% improvement on medical multimodal question answering, 15.5-18.1% improvement on chest X-ray finding classification, and 10.8% improvement on agentic evaluations compared to the base models. Fine-tuning MedGemma further improves performance in subdomains, reducing errors in electronic health record information retrieval by 50% and reaching comparable performance to existing specialized state-of-the-art methods for pneumothorax classification and histopathology patch classification. We additionally introduce MedSigLIP, a medically-tuned vision encoder derived from SigLIP. MedSigLIP powers the visual understanding capabilities of MedGemma and as an encoder achieves comparable or better performance than specialized medical image encoders. Taken together, the MedGemma collection provides a strong foundation of medical image and text capabilities, with potential to significantly accelerate medical research and development of downstream applications. The MedGemma collection, including tutorials and model weights, can be found at https://goo.gle/medgemma.

Beyond Task Performance: Evaluating and Reducing the Flaws of Large Multimodal Models with In-Context Learning

Mustafa Shukor, Alexandre Rame, Corentin Dancette, Matthieu Cord

Following the success of Large Language Models (LLMs), Large Multimodal Models (LMMs), such as the Flamingo model and its subsequent competitors, have started to emerge as natural steps towards generalist agents. However, interacting with recent LMMs reveals major limitations that are hardly captured by the current evaluation benchmarks. Indeed, task performances (e.g., VQA accuracy) alone do not provide enough clues to understand their real capabilities, limitations, and to which extent such models are aligned to human expectations. To refine our understanding of those flaws, we deviate from the current evaluation paradigm, and (1) evaluate 10 recent open-source LMMs from 3B up to 80B parameter scale, on 5 different axes; hallucinations, abstention, compositionality, explainability and instruction following. Our evaluation on these axes reveals major flaws in LMMs. While the current go-to solution to align these models is based on training, such as instruction tuning or RLHF, we rather (2) explore the training-free in-context learning (ICL) as a solution, and study how it affects these limitations. Based on our ICL study, (3) we push ICL further and propose new multimodal ICL variants such as; Multitask-ICL, Chain-of-Hindsight-ICL, and Self-Correcting-ICL. Our findings are as follows. (1) Despite their success, LMMs have flaws that remain unsolved with scaling alone. (2) The effect of ICL on LMMs flaws is nuanced; despite its effectiveness for improved explainability, answer abstention, ICL only slightly improves instruction following, does not improve compositional abilities, and actually even amplifies hallucinations. (3) The proposed ICL variants are promising as post-hoc approaches to efficiently tackle some of those flaws. The code is available here: https://github.com/mshukor/EvALign-ICL.

Diversity-Rewarded CFG Distillation

Geoffrey Cideron, Andrea Agostinelli, Johan Ferret, Sertan Girgin, Romuald Elie, Olivier Bachem, Sarah Perrin, Alexandre Ramé

Generative models are transforming creative domains such as music generation, with inference-time strategies like Classifier-Free Guidance (CFG) playing a crucial role. However, CFG doubles inference cost while limiting originality and diversity across generated contents. In this paper, we introduce diversity-rewarded CFG distillation, a novel finetuning procedure that distills the strengths of CFG while addressing its limitations. Our approach optimises two training objectives: (1) a distillation objective, encouraging the model alone (without CFG) to imitate the CFG-augmented predictions, and (2) an RL objective with a diversity reward, promoting the generation of diverse outputs for a given prompt. By finetuning, we learn model weights with the ability to generate high-quality and diverse outputs, without any inference overhead. This also unlocks the potential of weight-based model merging strategies: by interpolating between the weights of two models (the first focusing on quality, the second on diversity), we can control the quality-diversity trade-off at deployment time, and even further boost performance. We conduct extensive experiments on the MusicLM (Agostinelli et al., 2023) text-to-music generative model, where our approach surpasses CFG in terms of quality-diversity Pareto optimality. According to human evaluators, our finetuned-then-merged model generates samples with higher quality-diversity than the base model augmented with CFG. Explore our generations at https://google-research.github.io/seanet/musiclm/diverse_music/.

Conditional Language Policy: A General Framework for Steerable Multi-Objective Finetuning

Kaiwen Wang, Rahul Kidambi, Ryan Sullivan, Alekh Agarwal, Christoph Dann, Andrea Michi, Marco Gelmi, Yunxuan Li, Raghav Gupta, Avinava Dubey, Alexandre Ramé, Johan Ferret, Geoffrey Cideron, Le Hou, Hongkun Yu, Amr Ahmed, Aranyak Mehta, Léonard Hussenot, Olivier Bachem, Edouard Leurent

Reward-based finetuning is crucial for aligning language policies with intended behaviors (e.g., creativity and safety). A key challenge is to develop steerable language models that trade-off multiple (conflicting) objectives in a flexible and efficient manner. This paper presents Conditional Language Policy (CLP), a general framework for finetuning language models on multiple objectives. Building on techniques from multi-task training and parameter-efficient finetuning, CLP learn steerable models that effectively trade-off conflicting objectives at inference time. Notably, this does not require training or maintaining multiple models to achieve different trade-offs between the objectives. Through extensive experiments and ablations on two summarization datasets, we show that CLP learns steerable language models that outperform and Pareto-dominate the existing approaches for multi-objective finetuning.

Gemma 3 Technical Report

Gemma Team, Aishwarya Kamath, Johan Ferret, Shreya Pathak, Nino Vieillard, Ramona Merhej, Sarah Perrin, Tatiana Matejovicova, Alexandre Ramé, Morgane Rivière, Louis Rouillard, Thomas Mesnard, Geoffrey Cideron, Jean-bastien Grill, Sabela Ramos, Edouard Yvinec, Michelle Casbon, Etienne Pot, Ivo Penchev, Gaël Liu, Francesco Visin, Kathleen Kenealy, Lucas Beyer, Xiaohai Zhai, Anton Tsitsulin, Robert Busa-Fekete, Alex Feng, Noveen Sachdeva, Benjamin Coleman, Yi Gao, Basil Mustafa, Iain Barr, Emilio Parisotto, David Tian, Matan Eyal, Colin Cherry, Jan-Thorsten Peter, Danila Sinopalnikov, Surya Bhupatiraju, Rishabh Agarwal, Mehran Kazemi, Dan Malkin, Ravin Kumar, David Vilar, Idan Brusilovsky, Jiaming Luo, Andreas Steiner, Abe Friesen, Abhanshu Sharma, Abheesht Sharma, Adi Mayrav Gilady, Adrian Goedeckemeyer, Alaa Saade, Alex Feng, Alexander Kolesnikov, Alexei Bendebury, Alvin Abdagic, Amit Vadi, András György, André Susano Pinto, Anil Das, Ankur Bapna, Antoine Miech, Antoine Yang, Antonia Paterson, Ashish Shenoy, Ayan Chakrabarti, Bilal Piot, Bo Wu, Bobak Shahriari, Bryce Petrini, Charlie Chen, Charline Le Lan, Christopher A. Choquette-Choo, CJ Carey, Cormac Brick, Daniel Deutsch, Danielle Eisenbud, Dee Cattle, Derek Cheng, Dimitris Paparas, Divyashree Shivakumar Sreepathihalli, Doug Reid, Dustin Tran, Dustin Zelle, Eric Noland, Erwin Huizenga, Eugene Kharitonov, Frederick Liu, Gagik Amirkhanyan, Glenn Cameron, Hadi Hashemi, Hanna Klimczak-Plucińska, Harman Singh, Harsh Mehta, Harshal Tushar Lehri, Hussein Hazimeh, Ian Ballantyne, Idan Szpektor, Ivan Nardini, Jean Pouget-Abadie, Jetha Chan, Joe Stanton, John Wieting, Jonathan Lai, Jordi Orbay, Joseph Fernandez, Josh Newlan, Ju-yeong Ji, Jyotinder Singh, Kat Black, Kathy Yu, Kevin Hui, Kiran Vodrahalli, Klaus Greff, Linhai Qiu, Marcella Valentine, Marina Coelho, Marvin Ritter, Matt Hoffman, Matthew Watson, Mayank Chaturvedi, Michael Moynihan, Min Ma, Nabila Babar, Natasha Noy, Nathan Byrd, Nick Roy, Nikola Momchev, Nilay Chauhan, Noveen Sachdeva, Oskar Bunyan, Pankil Botarda, Paul Caron, Paul Kishan Rubenstein, Phil Culliton, Philipp Schmid, Pier Giuseppe Sessa, Pingmei Xu, Piotr Stanczyk, Pouya Tafti, Rakesh Shivanna, Renjie Wu, Renke Pan, Reza Rokni, Rob Willoughby, Rohith Vallu, Ryan Mullins, Sammy Jerome, Sara Smoot, Sertan Girgin, Shariq Iqbal, Shashir Reddy, Shruti Sheth, Siim Põder, Sijal Bhatnagar, Sindhu Raghuram Panyam, Sivan Eiger, Susan Zhang, Tianqi Liu, Trevor Yacovone, Tyler Liechty, Uday Kalra, Utku Evci, Vedant Misra, Vincent Roseberry, Vlad Feinberg, Vlad Kolesnikov, Woohyun Han, Woosuk Kwon, Xi Chen, Yinlam Chow, Yuvein Zhu, Zichuan Wei, Zoltan Egyed, Victor Cotruta, Minh Giang, Phoebe Kirk, Anand Rao, Kat Black, Nabila Babar, Jessica Lo, Erica Moreira, Luiz Gustavo Martins, Omar Sanseviero, Lucas Gonzalez, Zach Gleicher, Tris Warkentin, Vahab Mirrokni, Evan Senter, Eli Collins, Joelle Barral, Zoubin Ghahramani, Raia Hadsell, Yossi Matias, D. Sculley, Slav Petrov, Noah Fiedel, Noam Shazeer, Oriol Vinyals, Jeff Dean, Demis Hassabis, Koray Kavukcuoglu, Clement Farabet, Elena Buchatskaya, Jean-Baptiste Alayrac, Rohan Anil, Dmitry, Lepikhin, Sebastian Borgeaud, Olivier Bachem, Armand Joulin, Alek Andreev, Cassidy Hardin, Robert Dadashi, Léonard Hussenot